Dallas Clouatre, PhD
Last month, this column provided an overview for “Thinking About Cancer,” relying on information supplied in a book on prostate cancer that I co-authored several years ago. For those who would like to explore the topic of cancer in greater detail, that book is still available at amazon.com under the title, The Prostate Miracle: New Natural Therapies That Can Save Your Life. As noted in the previous column, researchers giving advice on preventing cancer usually present cancer as developing in three distinct stages: initiation, promotion, and progression. The existence of these stages suggests that there are distinct measures that can be taken to protect against cancer. This month, we will explore some options for preventing initiation and promotion as well as courses of action for those who already are beyond the “prevention” stage and want to be proactive in their own treatment.
A few years ago, I was asked to co-author a book on prostate cancer (The Prostate Miracle: New Natural Therapies That Can Save Your Life, available at amazon.com.) In researching that book, I read a large body of material on cancer in general and came to the conclusion that cancer, or, really, cancer-like and cancer-related changes in the body, often are more environmental than genetic. They are closely related to our habits and our environment and these factors go a long way towards determining whether genetic risks are activated or controlled. Many women at this point in time may not find such a conclusion at all surprising—more than a decade ago, analyses of large trials using hormone replacement therapy to treat menopause revealed that hormone replacement quite significantly increased one or more “women’s” cancers. Moreover, a radical reduction in the use of hormone replacement therapy since that time has been rewarded with a similar reduction in female cancers, thus providing convincing proof for this line of argument. We do not seem to have such an undeniable “smoking gun” for prostate cancer, yet environmental factors (low vitamin D, exposure to environmental or “xeno” estrogens) are clearly at work in this “male” cancer, as well.
Over the years, a great many weight loss products have come and gone. Each new weight loss season, a fresh crop of dragon slayers is announced and by the end of the year, most of these have slipped into well-deserved oblivion. Turnover on this level tends to obscure the fact there are some approaches that work and that the fundamentals of weight control are reasonably well established, even if products are not.
In his book, Good Calories, Bad Calories: Challenging the Conventional Wisdom on Diet, Weight Control and Disease, Gary Taubes responds concisely regarding the fundamental question of what regulates fat accumulation, which is to say, weight gain. Taubes answers simply, “This was elucidated by 1965 and has never been controversial. Insulin is the principle regulator of fat metabolism...”
The importance of minerals in the diet was brought home to me years ago in the form of an animal study on the effects on serum cholesterol of dietary magnesium in diets that included either butter or polyunsaturated fat in the form of corn oil margarine. Pigs were chosen because their gastrointestinal tracts are very similar to those of humans and they respond to dietary factors similarly, as well. The surprising finding was that the level of dietary magnesium was more significant to plasma total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) levels than was butter or margarine. When the intake of magnesium was increased substantially (doubled) beyond what was assumed to be an adequate amount for pigs, there no longer was any difference in serum levels of blood lipids between animals ingesting the two different fats.1 The meaning of the study was clear. Mammals possess enzymes known as desaturases and these mineral-dependent enzymes are sufficient to control serum lipids within “normal” ranges. Helping the body to handle fats is merely one of the vast number of roles played by dietary minerals and trace minerals.
More than fifty years ago, a special extract made from rye and other pollens was first discovered to provide dramatic relief not only from the symptoms of benign prostatic hyperplasia (BPH), but also from the symptoms of prostatitis and prostatodynia, two other common prostate conditions. The story of the discovery of these health benefits of pollen extract is wonderfully recounted in the book, The Prostate Cure, written by Harry G. Preuss, MD, and Brenda Adderly, MHA. However, the story of pollen extract does not end with its benefits in these conditions or even with its benefits in the area of prostate health. Recent research has shown that pollen extract inhibits the growth of some forms of cancer, that it activates important protective liver enzymes, and that it protects against damage to the heart and may improve athletic performance.
Not a month goes by without headlines in the media proclaiming either that vitamins do amazing things or that they do nothing at all. Such concerns no longer are limited to those whose jobs are to raise such issues. Individuals purchasing health foods and related products increasingly are asking questions about the cost and effectiveness of supplements. Likewise, governmental watchdog agencies, such as the Food and Drug Administration (FDA), expect that the manufacturers and marketers of nutrients and herbs be able to back up claims with sound research. Total Health Magazine Online took an in-depth look at some of the issues back in 2011, for which see “Are Vitamin Supplements Safe?”
The health of the body is often reflected in the eyes. Circulatory problems, which are hidden elsewhere in the body, can manifest visibly in these organs. Similarly, the antioxidant status of the aging body often will have a profound effect upon the eyes. Age-related macular degeneration (AMD, a deterioration in the retina at the point at which images are focused) is a typical result of the aging process, as the formation of cataracts (opaque defects in the transparency of the lens of the eye). Prevent Blindness America estimates that AMD may affect 13 million individuals in this country. Cataracts impair the vision of roughly four million Americans. Some authorities estimate that thirty percent of all adults aged 70 and older suffer from some form of vision impairment.
Culinary herbs seldom began their human histories as mere flavorings. Indeed, the kitchen herb and spice rack could reasonably be dubbed the kitchen medicine chest and several useful books have done just that. Oregano is a good example of a culinary herb that leads a double life. In much of the world, this plant continues to be used not just to flavor and preserve food, but also to disinfect surfaces and wounds, to calm the stomach, and much more. For some of these purposes, oregano extracts may still be as good or better than many of the modern alternatives. In other words, the health benefits of oregano are not only "traditional" or "folk remedies."
Milk thistle, as is true of similarly classic liver tonics from the Chinese tradition, such as bupleurum, has occupied a central spot in herbalism for good reasons, many of which remain true today.
This herbal tonic generally ranks high in recognition and sales with the American public in comparison with other botanical products. Nevertheless, its sales here are small on a per capita basis compared with, say, Germany, perhaps as little as 25 percent of what might be expected. Both old research and new suggest that milk thistle deserves even wider appreciation.
The role of probiotics in maintaining health no longer is quite as obscure to Americans as it once was. Yogurt is touted in TV and print advertisements; sometimes, an actor on a show even will play up his or her fondness for yogurt to make a fictional character more human and personable. Similarly, probiotics no longer are found only in health food stores—most drugstores sell at least two or three brands. This situation certainly is an improvement in providing sources of support for digestive health. However, it also may be a bit misleading.
Stress, anxiety and depression are major factors in the lives of many of us. An estimated 9.1 percent of the population of the U.S. suffers from depression every year, which translates to approximately 28 million Americans suffering from depression for at least two weeks with significant symptoms each year. This figure does not include greater or lesser degrees of apathy. Major depression claims 4.1 percent of the population, which is to say, from 12 to 13 million sufferers.1
Even those who are not depressed according to the textbook definition often are not home free. All too often individuals find themselves on a “seesaw” in which they swing from frenetic activity to lethargy and back. Living habits, choices of foods and beverages, the lack of physical exercise and other everyday factors can play a big role in mood swings, but it can be hard to get back into balance once equilibrium is lost. Fortunately, the proper use of nutrients and herbs can go a long way towards helping us to “beat the blues” naturally without resorting to Prozac and other drugs, most of which have numerous and unpleasant side effects.
Toxins come in a variety of forms. Our environment is full of them, and not all of these are man-made. Many toxins are found in everyday foods. Worse yet, some of the most dangerous toxins—toxins linked to breast and prostate cancers, for instance—are made in our own bodies. Of course, we are not without inborn defenses against toxic assaults. Indeed, the liver, in particular, is an organ, which is equipped to deactivate and remove poisons from our systems.
The stakes are high in the fight against toxins. Cancers and cardiovascular disease are two common results of toxic assaults upon the cells. The best known of the toxic compounds are free radicals, molecules generally produced by the action of oxygen and which can attack cell membranes and cellular DNA (deoxyribonucleic acid, the “blue print” for cell functions and cell division). Antioxidants and free radical scavengers, such as the vitamins C and E, and plant compounds such the anthocyanidins and ellagic acid found in fruits and vegetables, prevent free radicals from causing damage to the tissues.
The Centers for Disease Control and Prevention (CDC) estimates that approximately six percent of Americans suffer from asthma. This is a surprisingly high figure and it is on the rise. It is surprisingly high in part because asthma is one of a number of health conditions that can be present, yet unrecognized, in both children and adults. Yet being out of sight is not the same as being benign. Nearly 500,000 Americans are hospitalized each year for asthma and more than 5,000 die from it.
In this age of marketing of new fruits of every stripe—“super,” “exotic,” “rainforest,” etc. — it is easy to overlook the fact the best of the fruits for many purposes may be those long known. Bilberry is a good example. Black currant is another. Also called the cassis berry (Ribes nigrum), black currant offers many benefits similar to those found with bilberry and blueberry. Indeed, the list of benefits is quite impressive and includes brain, digestive and eye health along with positive influences in the areas of asthma and overall lung function, colds and flu, and women’s health.
No one doubts that obesity is a problem in the United States. According to figures released by the Centers for Disease Control (CDC) in January 2010 analyzing the period 2007–2008, the prevalence of obesity was 32.2 percent among adult men and 35.5 percent among adult women. The age-adjusted prevalence of overweight and obesity combined was 68.0 percent overall; 72.3 percent among men, and 64.1 percent among women. That’s right: in 2008 an estimated 68 percent of Americans were overweight or obese! To put this in perspective, from 1960–2 to 2005–6, the prevalence of obesity increased from 13.4 to 35.1 percent in U.S. adults 20 to 74.7 years of age. Statistics for those overweight were in the same range. Within living memory, the proportion of Americans who are overweight and obese has more than doubled. Quite obviously, there has been no massive shift in genetics in the U.S. in the last 50 years, so what has caused such weight gain?
Bone health is one of the most widely written about topics in the United States and most of us, no doubt, feel we have a grasp of how to protect ourselves. Sadly, most of us would be wrong in judging our own risk of suffering from osteoporosis or related conditions and most of us would be wrong in evaluating which nutrients are most important for protecting bone health.
In mid-2012, Nestlé Health Science acquired a stake in Accera®, the U.S. maker of Axona®, a medical food targeted at people with mild to moderate Alzheimer’s. Aside from the fact that the purchase shows that Nestlé is placing a strategic bet on the future direction of medical food demand, this acquisition also is interesting for its potential validation of a tropical oil that alternately has been damned and praised for its role in health: coconut oil.
Recently, this magazine ran a series of articles on vitamin and mineral supplements addressing the seemingly simple question, “Who needs them?” This seemed like a good jumping off point. Whenever you look at a supplement, you ask yourself what benefits its various ingredients will deliver. One formula promises to provide insurance against a multitude of vitamin and mineral deficiencies, another to supply protection against stress, and a third claims to protect against, say, bone loss. Athletes, in particular, constantly push their bodies “to the edge,” and they rightly expect ergogenic aids to be just that—substances that improve the body’s capacity to engage in physical activities. Moreover, serious athletes and body builders often cross the line between training and over-training. Dietary supplements are expected to a variety of needs, both minor and major. However, is choosing a supplement merely a matter of finding one with ingredients that match perceived needs?
Back in the news is MSM (short for methylsulfonyl-methane, also known as dimethyl sulfone). MSM has generated broad anecdotal support for its benefits in cases of allergies, arthritis and joint pain. However, the list of conditions that are said to respond to MSM is much longer. Broadly speaking, MSM has been tested with clinical results in inflammation, joint and tissue pain, muscle spasms, hair and nail growth, even snoring! So just what is this compound and how does it work? Is it really a panacea?
Nature’s Sulfur Cycle
MSM’s initial popularity was due, in part, to the success of the booklet, “The MSM Miracle: Enhance Your Health with Organic Sulfur,” by Earl L. Mindell, R.PH., Ph.D. which was followed in 1999 by the definitive The Miracle of MSM (by Jacob, Lawrence and Zucker). However, the story of MSM dates back at least to the early 1960s. Unfortunately, these first suggestions of the nutritional and therapeutic potential of MSM were not immediately followed up. Yet another decade lapsed before real clinical studies began. The catalyst for renewed interest was a report presented at a meeting of the New York Academy of Sciences in the early 1980s. Since that time, thousands of patients have been given MSM under medical supervision to determine its benefits and side effects when given either by mouth or intravenously, with much of that work performed at the Oregon Health Sciences University. Hundreds of thousands more individuals have purchased MSM from health food store shelves.